Category Archives: Covid

pepermint patty and the constitution

 

ok so they have thrown out the constitution. there is nothing in the constitution that is about your health or the federal govt’s ability to mandate a health issue. and since there is nothing that according to the 10th amendment goes back to the states. and if its not in the states constitution it goes directly to the people.

what it’s ok as long as it is pot? but not ok if it is a worthless jab?

there has to be something about this jab that they put in it. I mean to exclude anyone that had the bug and natural immunity? the more I read the less I like the jab.

now even if you got the J&J they want you to get the moderna or pfizer jab to boost it??? really? just what are they changing in the dna? what is this talk about graphine? or the microbes? i am discounting those for now, as i dont have enough info on it.  I will NEVER get the jab from my initial research on it. see blog post 41.

This is a fight for our country. this is a fight to maintain the Constitution. This is a fight for our freedoms.

Glenn

Biden EO on vax mandate

ok i noticed that there have been a lot of people saying biden didnt make a vax mandate. well , errr yes he did, i did the dive today. the eo is https://www.whitehouse.gov/briefing-room/presidential-actions/2021/09/09/executive-order-on-ensuring-adequate-covid-safety-protocols-for-federal-contractors/ then it gives control to some agency i never heard of and here is their guidance – https://www.saferfederalworkforce.gov/downloads/Draft%20contractor%20guidance%20doc_20210922.pdf now , this guidance does not take in the best medical advise as it gives NO leeway for those that had the bug already. and has a comply by date of dec 8. even though bidens eo says oct 15. and it is ONLY for government contractors. NOT the general public or other business’s . so a company that has no federal contracts does not need to comply.

covid and rna by a doctor

RW Malone MD@RobertMaloneMD

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Coronaviruses and other single stranded RNA viruses are classified as positive or negative stranded depending on the polarity of the RNA. One can think of RNA polarity as sort of like reading a sentence from left to right (positive polarity) or right to left (negative polarity). The machinery in cells that makes proteins from RNA reads the RNA (message) from left to right. So, getting really technical, coronaviruses are a type of positive-polarity single-stranded enveloped RNA virus, which is to say that virus proteins can be produced directly from the RNA genome by reading it from left to right. The RNA does not have to go through another round of replication (as is required for negative-polarity RNA viral genomes) to get back to a form that can be read from left to right to produce proteins after infecting a cell. At a practical level, this also means that the RNA genome of a coronavirus can be infectious; the RNA alone, if transferred into a cell, can cause that cell to produce complete and infectious new coronaviruses. This is why mRNA vaccines only use a fragment of the mRNA genome, so that the mRNA can not reproduce virus.

Using RNA as the genetic material is very efficient (a single strand is easier and cheaper to make than two!), but it is also very likely to develop errors during replication relative to using double stranded DNA (like human beings use). Among other problems with this viral strategy is that this means that viruses that use RNA often mutate very fast. Good thing that human beings use DNA to store their genetic information!

RNA viruses make this high mutation rate work for them. The high mutation rate of RNA viruses is one reason why it is difficult to make effective vaccines against many of these types of viruses.

Positive-sense RNA viruses account for a large fraction of all known human viruses, including many well-known pathogens such as HIV (the AIDS virus), hepatitis C virus (liver cancer), rhinoviruses (common cold), West Nile virus, Dengue virus, Zika, SARS and MERS coronaviruses, and COVID-19. Even though the single stranded RNA strategy comes with the problem of high mutation rate, these viruses replicate so efficiently, and produce so many viruses so fast, that it does not slow them down. In fact, the high mutation rate is sort of an advantage for viruses- it makes it easy for them to evolve and adapt to a new host (you and me) very rapidly, and to adapt to escape immunity in the animals that they infect (including us).

There have been reports of the virus’ genome being different at various time points within an individual. Another RNA virus with this capability that we are all familiar with is HIV.

(For those of you paying attention, smash these ideas together with 1) escape mutants against a vaccine with a target of a single protein (spike in this case) and 2) why we don’t have a vaccine for HIV and the common cold…)

Pfizer approval

Yes the FDA did approve the shot for covid. with the brand name COMIRNATY. there is a bit of confusion because they also issued an eua at the same time to expand the use of this drug.

here is the original approval August 23, 2021 Approval Letter – Comirnaty (fda.gov)

this was for adults 16 and up for 2 shots. then they issued another eua to approve other uses that the company did not show proof for yet. that eua is Pfizer-BioNTech COVID-19 Vaccine EUA LOA reissued August 23 2021 (fda.gov)

in that eua they said they are approving uses beyond the original approval conditionally, while they wait for studies that Pfizer needs to do. here is the sentence that everyone is missing-

and to authorize use of COMIRNATY (COVID-19 Vaccine, mRNA) under this EUA for
certain uses that are not included in the approved BLA.

everyone is getting confused due the language they used. hard reading to be sure, even I missed it the first couple times I read it.

so yes they have approved the drug Comirnaty for covid in ages 16 and up for 2 shots.

(a note that Comirnaty is not the original Pfizer shot but is substantially the same and interchangeable according to the eua.)

(I am still not getting it, i don’t care about the approval. the FDA has been wrong before.)hey said they are approving uses beyond the original approval conditionally, while they wait for studies that Pfizer needs to do. here is the sentence that everyone is missing-

and to authorize use of COMIRNATY (COVID-19 Vaccine, mRNA) under this EUA for
certain uses that are not included in the approved BLA.

everyone is getting

natural immunity compared to vaccine-induced immunit

Covid-19 natural immunity compared to vaccine-induced immunity: The definitive summary | Sharyl Attkisson

While it’s impossible to know whether that’s the case, public health officials are grappling with the reality of an increasing number of fully-vaccinated Americans coming down with Covid-19 infections, getting hospitalized, and even dying of Covid. The Centers for Disease Control (CDC) insists vaccination is still the best course for every eligible American. But many are asking if they have better immunity after they’re infected with the virus and recover, than if they’re vaccinated.

Increasingly, the answer within the data appears to be ”yes.”

Why does CDC seem to be “ignoring” natural immunity?

In fact, some medical experts have said they’re confounded by public health officials’ failure to factor natural and virus-acquired immunity into the Covid equation. Public and media narratives often press the necessity of “vaccination for all,” chiding states where vaccination rates are lowest. And they use vaccination rates and Covid case counts as inverse indicators of how safe it is in a particular state: high vaccination rate = high safety; high case counts = low safety (they claim).

(Read and Watch) Exclusive Covid-19 Origins Investigation

However, vaccination rates alone tell little about a population’s true immune-status. And where high Covid case counts occur, it ultimately means a larger segment of that community ends up better-protected, vaccines aside. That’s according to virologists who point out that fighting off Covid, even without developing any symptoms, leaves people with what’s thought to be more robust and longer-lasting immunity than the vaccines confer.

The vaccine immunity problem

Hard data counters widespread public misinformation that claimed “virtually all” patients hospitalized and dying of Covid-19 are unvaccinatedPfizer and Moderna had claimed their vaccines were “100% effective” at preventing serious illness. Many in the media even popularized a propaganda phrase designed to push more people to get vaccinated: “pandemic of the unvaccinated.”

Not so, says CDC and other data.

Recent CDC data found that 74% of those who tested positive for Covid-19 in a Massachusetts analysis had been fully-vaccinated. Equally as troubling for those advocating vaccination-for-all: four out of five people hospitalized with Covid were fully-vaccinated. And CDC said “viral load” — indicating how able the human host is to spread Covid-19 — is about the same among the vaccinated and unvaccinated. Contrary to the infamous misinformation by CDC Director Rochelle Walensky last May, vaccinated people can— and are— spreading Covid. (CDC officials later corrected Walensky’s false claim.)

(READ) Covid-19 Vaccine Analysis: the most common adverse events reported so far

CDC’s newest findings on so-called “breakthrough” infections in vaccinated people are mirrored by other data releases……..

for more click on the link above

research paper

SARS-COV-2 Vaccines and Neurodegenerative Disease

Wednesday, June 2nd 2021 Written By: Stephanie Seneff


Originally published on www.stephanieseneff.net

Since December 2021, when several novel unprecedented vaccines against SARS-CoV-2 began to be approved for emergency use, there has been a worldwide effort to get these vaccines into the arms of as many people as possible as fast as possible. These vaccines have been developed “at warp speed,” given the urgency of the situation with the COVID-19 pandemic. Most governments have embraced the notion that these vaccines are the only path towards resolution of this pandemic, which is crippling the economies of many countries.

Thus far, there are four different vaccines that have been approved for emergency use for protection against COVID-19 in the US and/or Europe. Two (the Moderna vaccine and the Pfizer/BioNTech vaccine) are based on mRNA technology, whereas the other two (produced by Johnson & Johnson and AstraZeneca) are based on a double-stranded DNA recombinant viral vector. The mRNA vaccines contain only the code for the SARS-CoV-2 envelope spike protein, whereas the DNA-based vaccines both contain an adenovirus viral vector that has been augmented with DNA that codes for the SARS-CoV-2 spike protein. The DNA-based vaccines have a certain advantage over the RNA-based vaccines in that they do not have to be stored at deep-freeze temperatures, because double-stranded DNA is much more stable than single-stranded RNA. But a disadvantage is that those who have been exposed to natural forms of the adenovirus have antibodies to the virus that will likely block the synthesis of the spike protein, and therefore not afford protection against SARS-CoV-2.

In this regard, the AstraZeneca (AZ) vaccine has a slight advantage over the Johnson & Johnson (J&J) vaccine because the virus normally infects chimpanzees rather than humans, so fewer people are likely to have been exposed to it [1, 2]. On the other hand, several studies have shown that viruses that normally infect one species can cause tumors if they are injected into a different species. For example, a human adenovirus injected into baboons caused retinoblastoma (cancer of the eye) in the baboons [3]. So, it can’t be ruled out that the AZ vaccine could lead to cancer.

People don’t realize that these vaccines are vastly different from the many childhood vaccines we are now used to getting early in life. I find it shocking that the vaccine developers and the government officials across the globe are wrecklessly pushing these vaccines on an unsuspecting population. Together with Dr. Greg Nigh, I recently published a peer-reviewed paper on the technology behind the mRNA vaccines and the many potentially unknown consequences to health [4]. Such unprecedented vaccines normally take twelve years to develop, with only a 2% success rate, but these vaccines were developed and brought to market in less than a year. As a consequence, we have no direct knowledge of any effects that the vaccines might have on our health over the long term. However, knowledge about how these vaccines work, how the immune system works and how neurodegenerative diseases come about can be brought to bear on the problem in order to predict potential devastating future consequences of the vaccines.

The mRNA in these vaccines codes for the spike protein normally synthesized by the SARS-CoV-2 virus. However, both the mRNA and the protein it produces have been changed from the original version in the virus with the intent to increase rate of production of the protein in an infected cell and the durability of both the mRNA and the spike protein it codes for. Additional ingredients like cationic lipids and polyethylene glycol are also toxic with unknown consequences. The vaccines were approved for emergency use based on grossly inadequate studies to evaluate safety and effectiveness.

Our paper showed that there are several mechanisms by which these vaccines could lead to severe disease, including autoimmune disease, neurodegenerative diseases, vascular disorders (hemorrhaging and blood clots) and possibly reproductive issues. There is also the risk that the vaccines will accelerate the emergence of new strains of the virus that are no longer sensitive to the antibodies produced by the vaccines. When people are immune compromised (e.g., taking chemotherapy for cancer), the antibodies they produce may not be able to keep the virus in check because the immune system is too impaired. Just as in the case of antibiotic resistance, new strains evolve within an infected immune-compromised person’s body that produce a version of the spike protein that no longer binds with the acquired antibodies. These new strains quickly come to dominate over the original strain, especially when the general population is heavily vaccinated with a vaccine that is specific to the original strain. This problem is likely going to necessitate the repeated rollout of new versions of the vaccine at periodic intervals that people will have to receive to induce yet another round of antibody production in an endless game of cat and mouse.

Like the mRNA vaccines, the DNA vaccines are based on novel biotech gene editing techniques that are brand new, so they too are a massive experiment unleashed on a huge unsuspecting population, with unknown consequences. Both DNA vector vaccines have been associated with a very rare condition called thrombocytopenia, in which platelet counts drop precipitously, resulting in system-wide blood clots and a high risk of cerebral hemorrhaging [5]. This is likely due to an autoimmune reaction to the platelets, and it comes with a high risk of mortality. In the case of the AZ vaccine, this has caused over 20 European countries to temporarily pause their vaccination programs [6]. And the United States called a temporary halt on the J&J vaccine.

Even experts don’t really understand the mechanism as of now, although a fascinating theory to explain this depends on the fact that DNA vector vaccines require the DNA to be copied into RNA in the nucleus, and this presents the possibility of producing an incomplete copy, generated through “splice variants,” that is missing the code for attaching to the membrane [7]. These soluble partial sequences wander off to other parts of the body and bind to ACE2 receptors throughout the vasculature. Antibodies to these ACE2-bound partial spike fragments cause an acute inflammatory response that results in disseminated intravascular coagulation (DIC).

How to Make an Adenovirus DNA Vector Vaccine 

The adenovirus vaccines are created through techniques that the average citizen can’t possibly fathom could even exist. For the AZ vaccine, the bulk of the DNA in the vaccine codes for the various proteins that are needed by a strain of adenovirus that mainly infects chimpanzees and causes cold-like symptoms [1]. However, it is not a “normal” version of this cold virus. First of all, it has been stripped of certain genes that it needs in order to replicate, and for this reason it is referred to as an “adenovirus vector.” This defect, it is argued, keeps it from actually infecting the vaccinated patient. Secondly, it is modified, through gene editing techniques, to create a recombinant version of the virus that contains the complete coding sequence for the SARS-CoV-2 spike protein, spliced into its DNA sequence – the same protein that the RNA vaccines code for. The recombinant DNA is a linear double-stranded DNA sequence where proteins from two different species are integrated through gene editing.

Since this virus can’t proliferate, it is difficult to manufacture large quantities of it. But they solved this problem by making use of a genetically modified version of a human cell line, called HEK (human embryonic kidney) 293 cells, where the human cell’s DNA was transfected long ago with fragments of the genome of an adenovirus – conveniently providing the defective recombinant virus with the missing proteins it needs to be able to proliferate [8]. Within a culture of these HEK 293 cells, the virus can replicate, assisted by the proteins that are produced by the host cells. The HEK 293 cells originally came from a kidney of an aborted fetus, and it has been maintained in culture ever since the 1970s, because it was modified to become immortal, with the help of the adenovirus. Although it was obtained from a kidney, it is not a kidney cell. In fact, it has many properties that are characteristic of a neuronal stem cell [9]. The fact is, they don’t really know what kind of cell it is. The ability of a cell line to survive indefinitely is a feature of tumor cells. Although the vaccine is “purified” during the processing, there is no guarantee that it is not contaminated with remnants from the host cells, i.e., human DNA of a neuronal tumor cell line. It does not seem like a good idea to inject the DNA of a human tumor cell into anyone.

The J&J vaccine has a very similar manufacturing process, except with a different adenovirus strain and a different human host cell. For J&J, the host cell is another fetal cell line harvested long ago and made immortal through the incorporation of adenovirus genes into the host human genome. This cell line was taken from the retina of the eye of the fetus.

The Spike Protein is Toxic 

The COVID-19 vaccines are all based on supplying genetic code to produce the spike protein that is the main constituent of the SARS-CoV-2 protein cage that encloses its RNA contents. Both the DNA vector and the RNA vaccines induce the vaccine-infected cell to manufacture many copies of the spike protein according to the code. Through experimentation, researchers have determined that the spike protein is toxic even when introduced all by itself. In a revealing experiment, researchers injected spike protein into hamsters, and found that it was taken up by endothelial cells lining the blood vessels, via ACE2 receptors [10]. This caused a downregulation of ACE2, which had significant effects on the metabolic policy in the cells. In particular, it inhibited the synthesis of mitochondria, and caused the existing mitochondria to fragment. Mitochondria are the organelles in the cell that produce large quantities of ATP (the energy currency of cells) by oxidizing nutrients, while consuming oxygen and producing water and carbon dioxide. The spike protein reduced the production of ATP by mitochondria and increased glycolysis — the alternative, much less efficient, way to produce ATP without using oxygen. This metabolic change towards getting energy through glycolysis is a characteristic feature of cancer cells and of neurons in neurodegenerative diseases such as Alzheimer’s.

In another experiment, researchers showed that spike protein can cross the blood-brain barrier in mice and be taken up by neurons throughout the brain [11]. This too is likely mediated by ACE2 receptors (which neurons also produce). These same researchers also showed that spike protein administered in the nose was able to reach the brain by traveling along the olfactory nerve. When they induced inflammation in the brain through exposure to lipopolysaccharide (LPS), they saw an increased uptake of spike protein into the brain, which they hypothesized was caused by increased leakiness in the barrier. As you will see, these points become important when we later consider what happens following a SARS-CoV-2 vaccine, which is designed to induce inflammation.

Many people suffering from COVID-19 have experienced symptoms characteristic of the central nervous system such as headache, nausea, dizziness, fatal brain blood clots and encephalitis. In an advanced 3D microfluid model of the human BBB, researchers in the United States showed that the spike protein by itself disrupts the blood brain barrier by inducing an inflammatory state, and they proposed that this could be the source of such symptoms [12].

A published preprint found widespread expression of ACE2 in many parts of the brain. ACE2 was expressed in astrocytes, pericytes (cells that wrap around the endothelial cells lining capillary walls) and in endothelial cells — and all of these are key components of the blood-brain barrier [13]. Perhaps of even greater concern is that ACE2 was highly expressed in the substantia nigra, a brain-stem nucleus where damaged dopaminergic neurons lead to Parkinson’s disease.

Bell’s Palsy, Autism and Parkinson’s Disease 

In a paper aptly titled, “Is COVID-19 a Perfect Storm for Parkinson’s Disease?” researchers made a strong case for the possibility that we will see an increase in Parkinson’s disease in the future, due to the COVID-19 pandemic [14]. They refer to three separate cases where acute Parkinsonism developed shortly after a COVID-19 infection. They proposed that systemic inflammation caused by severe COVID-19 could trigger neuroinflammation in the substantia nigra, killing off dopaminergic neurons. These neurons express high levels of the ACE2 receptor, making them highly vulnerable to the spike protein. A viral infection is known to upregulate α-synuclein, which, in high concentrations, forms soluble oligomers that then precipitate out as fibrils and accumulate within “Lewy bodies” that are tightly linked to Parkinson’s disease. Further corroboration of this idea comes from a paper which demonstrated that an infection with SARS-CoV-2 causes brain inflammation in macaques and induces the formation of Lewy bodies [15].

Parkinson’s disease is the second most common neurodegenerative disorder and the most common neurodegenerative motor disorder. The root cause of nearly 90% of cases remains unknown, but it has been theorized that viral infections are often involved. It can be argued that the loss of a sense of smell and/or taste in association with COVID-19 is a sign of a Parkinsonian link, since this symptom is also an early sign of Parkinson’s disease [16].

The mRNA vaccines appear to disrupt the body’s ability to keep latent viruses from “waking up” and causing disease symptoms. This observation is based on the fact that shingles and facial palsy (Bell’s palsy) are being commonly reported in side-effect reports in the FDA’s Vaccine Adverse Event Reporting System. As of May 21, 2021, over 2500 reports of Bell’s palsy following COVID-19 vaccines had appeared in VAERS. A primary cause of Bell’s palsy is the activation of latent viral infections, most notably Herpes simplex and Varicella zoster, Varicella zoster is also the virus responsible for shingles.

While Bell’s palsy usually resolves over time, there can be some serious longer-term consequences. Pregnant women who are diagnosed with active herpes infections during pregnancy have a 2-fold increased risk of having an autistic male child from that pregnancy [17]. This should make a pregnant woman hesitate to get a SARS-CoV-2 vaccine. Bell’s palsy can also be a risk factor for Parkinson’s disease much later in life. A study on nearly 200 Parkinson’s disease patients compared with age- and gender-matched controls found that six of the Parkinson’s patients had had an earlier diagnosis of Bell’s palsy, whereas none of the control patients had [18]. There’s also a link between autism and Parkinson’s disease. A study on autistic adults over 39 years old found that one third of them had symptoms that meet the criteria for a Parkinson’s diagnosis [19].

Prion Diseases 

Prion diseases are a group of severe neurodegenerative diseases that are caused by misfolded prion proteins. The most common prion disease in humans is the always-fatal sporadic Creutzfeldt-Jakob disease (CJD), which accounts for more than 85% of the cases [20]. Prion diseases are more specifically called transmissible spongiform encephalopathies (TSEs), and infection can spread through exposure to misfolded proteins as “infective” agents, without requiring a live pathogen [20]. PrP is the name given to the specific prion protein associated with these TSEs. Misfolded PrP proteins act as a seed or catalyst that then recruits other molecules of PrP to misfold in the same way and glom together into pathogenic fibrils.

MADCOW, the disease that affected a large number of cows in Europe beginning in the 1990s, is probably the best-known TSE. While eating beef from an infected animal is a very rare risk factor, most cases of Creutzfeldt-Jakob disease occur for unknown reasons, and no other risk factors have been identified. A study based in Switzerland confirmed that many patients who died of Creutzfeldt-Jakob disease had detectable levels of a prion protein in their spleen and muscles, in addition to the olfactory lobe and the central nervous system [21]. More generally, diseases involving misfolded PrPs have consistently been found to involve an initial early phase of prion replication in the spleen which happens long before overt symptoms appear [22, 23]. This point becomes important when we consider whether the COVID-19 vaccines might cause prion diseases.

PrP has a unique feature that it contains multiple copies of a characteristic motif in its amino acid sequence that is called a “GxxxG” motif, also known as a “glycine zipper” [24]. These proteins normally fold into a characteristic shape called an alpha helix, which allows the protein to penetrate the plasma membrane. The glycines in the zipper motif play an essential role in cross-linking and stabilizing alpha helices [25]. This glycine zipper motif is also a common characteristic of many transmembrane proteins (proteins that cross the membrane of the cell).

Indeed, the coronavirus spike protein has a GxxxG motif in its transmembrane domain (specifically, GFIAG — glycine, phenylalanine, isoproline, alanine, glycine) [26]. There is a platform called “Uniprot” where you can look up the sequence of specific proteins. The Uniprot entry for the SARS-CoV-2 spike protein has five glycine zipper sequences altogether [27]. According to J. Bart Classen, the SARS-CoV-2 spike protein has the ability “to form amyloid and toxic aggregates that can act as seeds to aggregate many of the misfolded brain proteins and can ultimately lead to neurodegeneration.” [28]

Many neurodegenerative diseases have been linked to specific proteins that have prion-like properties, and these diseases are characterized as protein-misfolding diseases or proteopathies [29]. Like PrP, prion-like proteins become pathogenic when their alpha helices misfold as beta sheets, and the protein is then impaired in its ability to enter the membrane. These diseases include Alzheimer’s, amyotrophic lateral sclerosis (ALS), Huntington’s disease and Parkinson’s disease, and each of these is associated with a particular protein that misfolds and accumulates in inclusion bodies in association with the disease. We already saw that Parkinson’s disease is characterized by Lewy bodies in the substantia nigra that accumulate misfolded α-synuclein.

Glycines within the glycine zipper transmembrane motifs in the amyloid beta precursor protein (APP) play a central role in the misfolding of amyloid beta linked to Alzheimer’s disease (Decock et al., 2016). APP contains a total of four GxxxG motifs (one fewer than the spike protein).

A case study presented the case of a man who developed CKD simultaneously with symptomatic COVID-19. The authors proposed that infection with SARS-CoV-2 precipitates or accelerates neurodegenerative diseases [30]. A theoretical paper published by researchers in India showed that the spike protein binds to a number of aggregation-prone prion-like proteins, including amyloid beta, α-synuclein, tau, PrP and TDP-43. They argued that this could initiate aggregation of these proteins in the brain, leading to neurodegeneration [31].

Tracing the Vaccine Trail to the Spleen 

It is important to understand what happens to the contents of a vaccine after it is injected into the arm. Where does it travel in the body, and what does it do in the places where it settles in?

Vaccine developers are keen to know whether the vaccine induces a strong immune response, reflected in high antibody production against the spike protein, in the case of COVID-19 vaccines. And to do this, they need to trace its movement in the body.

CD8+ T-cells are cytotoxic immune cells that can kill cells that are infected with a virus. They detect an immune complex with viral proteins that are exposed on the surface of an infected cell. A study on an adenovirus-vector based vaccination of mice used clever methods to produce a marker that could track the activity of CD8+ T-cells in the lymph system and the spleen, in the days following vaccination [32]. It can be inferred that immune cells (antigen-presenting cells, where the “antigen” is the spike protein) were initially present at the arm muscle injection site and synthesized the virus spike protein from the vaccine DNA code, exposing it on their surface. Once activated by the foreign protein, they translocated into the draining lymph nodes and finally made their way to the spleen via the lymph system. The CD8+ T-cells are idly waiting within the lymphatics until they spot an infected immune cell. Researchers could detect activation of CD8+ immune cells over time and inferred that this was caused by the arrival of the contents of the vaccine to the site where these immune cells reside. Activated CD8+ T-cells first appeared in the draining lymph nodes, but after five days began to show up in the spleen. Their numbers there peaked sharply by 12 days and then remained high with a slow decay up to 47 days, when the researchers stopped looking. What this means is that the vaccine is picked up by antigen-presenting cells at the injection site and carried to the spleen via the lymph system. The carrier cells then hang out in the spleen for a long time. And this is where the danger lies in terms of the potential to cause prion disease.

In the paper that Greg Nigh and I published recently on the mRNA vaccines, we argued that the mRNA vaccines are rather perfectly set up to produce a very dangerous situation in the spleen that is poised to launch a prion disease. Given the fact that the DNA vector vaccines also end up concentrated in the spleen, I think that the same thing holds true for them as well. The spleen is where the action is for seeding misfolded prion proteins. The vaccine-infected cells have been programmed to produce large amounts of spike proteins. Prion proteins misfold into damaging beta-sheet oligomers when there are too many of them in the cytoplasm. Might the spike protein do the same?

Three out of the four COVID-19 vaccines currently on the market in the U.S. and Europe (Pfizer, Moderna, and J&J) use a genetic code for the spike protein that has been slightly tweaked, in order to produce a more potent antibody response [33]. Normally, after binding to the ACE2 receptor, the spike protein spontaneously changes its shape in a dramatic way in order to fuse with the membrane of the cell. In a Web publication, Ryan Cross described this action very graphically based on a spring-like model, as follows: “When the spike protein binds to a human cell, that spring is released, and the two helices and the loop straighten into one long helix that harpoons the human cell and pulls the virus and human membranes close together until they fuse.” [33]. As Cross explains, through trial and error, but taking structural information into account, researchers came up with the idea of swapping out two adjacent amino acids for prolines in the membrane fusion domain in order to stabilize the shape of the spike protein in its pre-fusion form. In this form, it exposes critical antigenic areas, and this assures more rapid formation of matching antibodies, the only goal of the vaccine design. This also prevents the protein from fusing with the plasma membrane of a host cell. I’d imagine that the spike protein attaches to the ACE2 receptor and then gets stuck there, like a sitting duck. But a worrisome thought is whether this open state, not fused with the membrane, might more closely resemble the shape of a misfolded prion-like protein like amyloid beta than does the collapsed shape it needs to go into the membrane?

Tetz and Tetz have argued in a published online preprint that prion-like domains in the spike protein enable higher affinity for the ACE2 receptor, making the virus more virulent than its earlier cousins [34]. These same authors published an earlier peer-reviewed journal paper where they observed that many other viruses have proteins in their coat that have distinct features of prion proteins [35].

Germinal Centers and Parkinson’s Disease 

Germinal centers in the spleen are a primary factory where antibodies against specific antigens (such as the spike protein) are manufactured and perfected. Makers of the mRNA vaccines were pleased to see that antigen-presenting cells (mainly dendritic cells), originally attracted to the site of the injection, take up the mRNA particles and then migrate via the lymph system to the spleen in high numbers and induce high levels of antibody production in these germinal centers [36].

Unfortunately, these same germinal centers are a primary site for the initiation of a process of producing and distributing misfolded prion proteins, often seeded by viral proteins, and triggered by an acute inflammatory response [37].

B cells, also known as B lymphocytes, are a type of immune cell that is the key player in the process that leads to the production of specific antibodies to a foreign antigen [38]. They originate from precursor cells in the bone marrow, and then migrate to the spleen and other lymphoid organs, where they bind to antigens presented to them by antigen-presenting cells, such as the dendritic cells. A maturation process beginning with a multipotent progenitor B cell ends with a mature “memory” B cell that has gone through a complex process to perfect its antibody production process to specifically match the antigen it has been assigned to (e.g., the spike protein). B cells also go through another process called class switching, which changes the type of antibody they produce from one class to another, without changing its specificity to the antigen.

Antibodies are also known as immunoglobulins (Igs), and the possible classes include IgM, IgG, IgA and IgE. IgM is the first immunoglobulin class that is produced (primarily in the spleen), and it is converted into IgG through class switching. IgG is the dominant class in the blood, making up 75% of the serum antibodies, and it is essential for clearing infections in the tissues. Long-lived mature memory B cells cruise the blood stream looking for any appearances of the antigen they have been assigned to, but they are useless for anything else. When the virus they’ve been trained to match mutates to the point where their antibodies no longer match well, they become useless even for the disease they’re trained to fight.

When mice are injected with PrP in the abdomen (intraperitoneal injection), the PrP shows up very quickly in the spleen. From there, the PrP travels along the spinal cord and the vagus nerve to reach the brain, causing prion disease [39]. As we will soon see, α-synuclein, the prion-like protein linked to Parkinson’s disease, also makes its way to the brain from the spleen along the vagus nerve. The mRNA vaccines set up perfect conditions in the spleen for the formation and distribution of conglomerates made up of misfolded α-synuclein, PrP and spike protein.

While α-synuclein causes neurodegenerative disease when it misfolds, in its normal shape it is an active participant in the immune response. α-Synuclein facilitates the processes that lead to antibody production in response to foreign antigens. Dendritic cells express α-synuclein, and it is upregulated (over-expressed) in response to stressors, such as the mRNA, the cationic lipids, and the PEG in the mRNA vaccines. Much can be learned by studying mice that have been genetically engineered to have a defective version of α-synuclein [40]. These mice have a decreased capacity to clear pathogens through phagocytosis, and an impairment in the ability to generate B cells from precursor stem cells. They also had a four-fold reduction in progenitor B cells in the bone marrow. The amount of immunoglobulin G was reduced compared to wildtype, suggesting impaired class switching. Altogether, they are unable to mount an effective immune response to antigens, whether they come from a natural threat or a vaccine.

Dendritic cells under stress accumulate prion proteins and release them into small lipid particles called exosomes, which are then distributed throughout the body, either along nerve fibers or in the general circulation [41]. There is reason to believe that these vaccines will accelerate the release of exosomes containing misfolded prion-like spike proteins that are being produced in large amounts under instruction from the vaccines. These spike proteins will act as seeds to cause α-synuclein and PrP to also misfold and form toxic oligomers together with the spike protein, which are released into the extracellular space as exosomes. These exosomes, released under the severe stress conditions induced by the vaccine, then carry prion proteins into the brain along the vagus nerve, to initiate prion diseases [42].

Impaired Immune Response due to Over-vaccination 

A characteristic of the elderly is an impaired ability to mount antibodies against new pathogenic threats, and this is reflected in a failure to generate protective antibodies in response to vaccination. It has been demonstrated in experiments with mice that aged mice have an overabundance of long-lived memory (antigen-experienced) B cells, and this is paired with an inability to generate new B cells from progenitor cells in the bone marrow, as well as impairment in the process of refinement of the antibody response in germinal centers in the spleen and the associated class switching that produces effective IgG antibodies [43, 44]. A significant reduction in the number of naive follicular B cells, combined with an impaired ability to convert them into mature memory B cells leaves these aged mice highly vulnerable to new infections. It is likely that the same principle applies to humans. A plausible conclusion is that aggressive vaccination campaigns accelerate the pace at which an individual’s immune system reaches an “aged” status due to exuberant generation of memory B cells in response to the artificial stimuli induced by repeated vaccination.

It has now been confirmed that the S1 component of the spike protein shows up in the blood one day after the first mRNA vaccine and remains detectable for up to a month after vaccination, becoming cleared as IgA and IgG antibodies become available [45]. For immune compromised people, it likely stays in the blood much longer, exposing all the tissues — the spleen, the heart, the brain, the gonads, etc. – to the toxic prion-like spike protein.

Today’s children are by far the most vaccinated generation in the history of humankind. If we decide in the near future to deliver a booster COVID-19 shot to them every year, as seems possible given the current climate of enthusiasm for these vaccines, are we inviting disaster for them in years to come? Will their immune system “age” much faster than that of previous generations, due to the exhaustion of the pool of progenitor B cells by all these vaccines? Will they succumb to Parkinson’s disease or other debilitating prion-based neurodegenerative diseases much sooner and in much greater numbers than previous generations? This is an experiment that I hope we finally decide not to carry out.

Summary 

There are many reasons to be wary of the COVID-19 vaccines, which have been rushed to market with grossly inadequate evaluation and aggressively promoted to an uninformed public, with the potential for huge, irreversible, negative consequences. One potential consequence is to exhaust the finite supply of progenitor B cells in the bone marrow early in life, causing an inability to mount new antibodies to infectious agents. An even more worrisome possibility is that these vaccines, both the mRNA vaccines and the DNA vector vaccines, may be a pathway to crippling disease sometime in the future. Through the prion-like action of the spike protein, we will likely see an alarming increase in several major neurodegenerative diseases, including Parkinson’s disease, CKD, ALS and Alzheimer’s, and these diseases will show up with increasing prevalence among younger and younger populations, in years to come. Unfortunately, we won’t know whether the vaccines caused this increase, because there will usually be a long time separation between the vaccination event and the disease diagnosis. Very convenient for the vaccine manufacturers, who stand to make huge profits off of our misfortunes — both from the sale of the vaccines themselves and from the large medical cost of treating all these debilitating diseases.


References https://www.greenmedinfo.com/blog/sars-cov-2-vaccines-and-neurodegenerative-disease

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this is a on going compendium of stuff about the vax’s

@sh_irredeemable

 

Until the end of April 2021, the Wikipedia page on RNA vaccines had the following summary:

“An RNA vaccine transfects molecules of synthetic RNA into human cells.

Little is known about the medium and longer-term side effects, however, autoimmunity, and reactogenicity (mainly from the lipid NANOPARTICLES), have been highlighted.”

Then on April 30th and May 14th, 2021, the fascist Josef Mengele Fauci Goebbels liars bastardized the page, inserted loads of text about the pharma Deep State narrative about how wonderful RNA vaccines are, and COMPLETELY REMOVED the facts about the lipid nanoparticles and unknown medium and longer-term side effects! The page now even calls those facts “misinformation” on social media.

And the narrative priests added this beauty: “Before 2020, no mRNA technology platform (drug or vaccine) had been authorized for use in humans, so there was a risk of unknown effects.” But magically everything was fixed in 2020!

We have regressed back to Medieval times when the Catholic Church corrupted and hid scientific facts to be fully aligned to establishment political narratives. An absolute disgrace!

————————————————————————————-

WATCH: Moderna Exec Talks About How MRNA Vaccines Edit Genetic Code

A video has surfaced from 2017 TedTalk which features a Moderna executive talking about MRNA vaccines altering genetic code.

Moderna Chief Medical Officer Confirms mRNA Injection For COVID-19 Can Change Your Genetic Code (banthis.tv)


Pfizer Executive Admits their Vaccine is not Designed to end the Pandemic But to Turn it into an Endemic

Pfizer Executive Admits their Vaccine is not Designed to end the Pandemic But to Turn it into an Endemic – Coercion Code – “Dark Times are upon us”


animal all died during testing

https://greatgameindia.com/covid-animal-trials-stopped/ vax trials on animals stopped after all the animals died. never got approved animal testing done, you are the experiment.


 

BOMBSHELL: Connecticut govt. secretly tells health care workers covid vaccines are DEADLY, but withholds the same information from the public

BOMBSHELL: Connecticut govt. secretly tells health care workers covid vaccines are DEADLY, but withholds the same information from the public – NaturalNews.com


 

 

J&J Vaccine over view

this is an ongoing paper describing the J&J vaccine for covid19.

I will be adding to this as I go with excerpts from the papers themselves. My initial reaction is good for the use of this vaccine. the vaccine is a standard style vaccine as far as I can tell thus far(inactive virus in a suspended medium) as opposed to a vaccine that modifies the RnA in your body with unknown long term effects.I will be adding in my comments as I go in italicized in parens.

after reading this data so far, this vaccine appears to be safer than other vaccines. tested across the globe, and with the same efficacy as a normal vaccine(67%). there appears to be no nuerological issues. yes there maybe an issue for those that are allergic to the growing agent.

the first part of this includes excerpts from the Jansen press release of the EUA. to be found at https://www.janssenlabels.com/emergency-use-authorization/Janssen+COVID-19+Vaccine-HCP-fact-sheet.pdf?fbclid=IwAR0HgvBeOMLuQtyZfkU06qXC-s7eQkb_rotJN7C5fb_tVFmp1KoQkW-MVeo

FACT SHEET FOR HEALTHCARE PROVIDERS ADMINISTERING VACCINE
(VACCINATION PROVIDERS)
EMERGENCY USE AUTHORIZATION (EUA) OF
THE JANSSEN COVID-19 VACCINE TO PREVENT CORONAVIRUS
DISEASE 2019 (COVID-19)
The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization
(EUA) to permit the emergency use of the unapproved product, Janssen COVID-19 Vaccine, for
active immunization to prevent COVID-19 in individuals 18 years of age and older.

The Janssen COVID-19 Vaccine is initially stored frozen by the manufacturer, then shipped at 2°C to 8°C (36°F to 46°F). If vaccine is still frozen upon receipt, thaw at 2°C to 8°C (36°F to 46°F). If
needed immediately, thaw at room temperature (maximally 25°C/77°F). At room temperature (maximally 25°C/77°F), a carton of 10 vials will take approximately 2 hours to thaw, and an
individual vial will take approximately 1 hour to thaw. Do not refreeze once thawed.

(unlike the other “vaccines” this one does not require adding suspension fluids, and comes shipped with full dose vials of 5 doses to a vial)

CONTRAINDICATION
Do not administer the Janssen COVID-19 Vaccine to individuals with a known history of a severe allergic reaction (e.g., anaphylaxis) to any component of the Janssen COVID-19 Vaccine (see Full
EUA Prescribing Information).

Severe allergic reactions, including one case of anaphylaxis in an ongoing open-label study in South Africa, have been reported following the Janssen COVID-19 vaccine administered in
clinical studies.

. A total of 43,783 individuals were enrolled in this study, of whom 21,895 adults aged 18 years and older received the Janssen COVID-19 Vaccine .The safety subset includes 6,736 individuals

Urticaria (all non-serious) was reported in five vaccinated individuals and 1 individual who received placebo in the 7 days following vaccination.

 

(What is urticaria?

Urticaria is also called hives. Hives can change size and shape, and appear anywhere on your skin. They can be mild or severe and last from a few minutes to a few days. Hives may be a sign of a severe allergic reaction called anaphylaxis that needs immediate treatment. Urticaria that lasts longer than 6 weeks may be a chronic condition that needs long-term treatment.)

In addition, an SAE of hypersensitivity, not
classified as anaphylaxis, was reported in 1 vaccinated individual with urticaria beginning two days following vaccination and angioedema of the lips with no respiratory distress beginning
four days following vaccination. The event was likely related to the vaccine.

• Thromboembolic events:
• Deep vein thrombosis: 6 events (2 serious; 5 within 28 days of vaccination) vs.
2 events (1 serious; 2 within 28 days of vaccination).
• Pulmonary embolism: 4 events (3 serious; 2 within 28 days of vaccination) vs. 1 event
(serious and within 28 days of vaccination).
• Transverse sinus thrombosis: 1 event (serious and within 28 days of vaccination) vs.
0.
• Seizures: 4 events (1 serious; 4 within 28 days of vaccination) vs. 1 event (0 serious and
0 within 28 days following vaccination).
• Tinnitus: 6 events (0 serious; 6 within 28 days of vaccination, including 3 within 2 days of
vaccination) vs. 0.

(these dont sound too serious compared to the numbers of 21k injections, though the tinitus is a strange one. and these appear at first glance to be less than the other “vaccines”)

(this is the important part, what is actually in the vaccine)

13 DESCRIPTION
The Janssen COVID-19 Vaccine is a colorless to slightly yellow, clear to very opalescent sterile suspension for intramuscular injection. It contains no visible particulates. The vaccine consists of
a replication-incompetent recombinant adenovirus type 26 (Ad26) vector expressing the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike (S) protein in a stabilized
conformation.

(This vaccine called Ad26.COV2.S uses some genetic material from the SARS-CoV-2 virus. More precisely, it uses the genetic code to make the spike protein, the protrusions that can be seen on the surface of the virus. The spike protein is used by many vaccines since this is what the virus uses to bind with human cells and initiate infection.)

(Adenoviruses are common viruses that cause a range of illness. They can cause cold-like symptoms, fever, sore throat, bronchitis, pneumonia, diarrhea, and pink eye (conjunctivitis).)

The Ad26 vector expressing the SARS-CoV-2 S protein is grown in PER.C6 TetR cells

(The PER.C6 cell line is derived from human embryonic retinal cells, originally from the retinal tissue of an 18 week old fetus aborted in 1985, PER.C6 cells grow well in suspension serum-free culture that is free of any animal-derived protein)(note from the readings I have done, no further children were killed after the initial cell line was cultured. I could be wrong but that is what I saw)

, in media containing amino acids and no animal-derived proteins. After propagation, the vaccine is
processed through several purification steps, formulated with inactive ingredients and filled into vials.
Each 0.5 mL dose of Janssen COVID-19 Vaccine is formulated to contain 5×1010 virus particles (VP) and the following inactive ingredients: citric acid monohydrate (0.14 mg), trisodium citrate
dihydrate (2.02 mg), ethanol (2.04 mg), 2-hydroxypropyl-β-cyclodextrin (HBCD) (25.50 mg), polysorbate-80 (0.16 mg), sodium chloride (2.19 mg). Each dose may also contain residual
amounts of host cell proteins (≤0.15 mcg) and/or host cell DNA (≤3 ng).(emp. added)
Janssen COVID-19 Vaccine does not contain a preservative.

The Janssen COVID-19 Vaccine is composed of a recombinant, replication-incompetent human adenovirus type 26 vector (not an mRnA but an inactive virus)that, after entering human cells, expresses the SARS-CoV-2 spike (S)
antigen without virus propagation. An immune response elicited to the S antigen protects against
COVID-19.

The median length of follow up for efficacy for individuals in the study was 8 weeks postvaccination. Vaccine efficacy for the co-primary endpoints against moderate to severe/critical
COVID-19 in individuals who were seronegative or who had an unknown serostatus at baseline
was 66.9% (95% CI: 59.0; 73.4) at least 14 days after vaccination and 66.1% (95% CI: 55.0; 74.8)
at least 28 days after vaccination (see Table 6).

(looking at the tables and stuff, it appears to be effective on the known variants of covid)

The EUA follows a unanimous vote by the U.S. FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) on February 26, 2021.

(as compared to the pfizer which had 4 members not recommending it)

I found the following-from

Johnson & Johnson Single-Shot COVID-19 Vaccine Candidate Unanimously Recommended for Emergency Use Authorization by U.S. FDA Advisory Committee | Johnson & Johnson (jnj.com)

Johnson & Johnson is committed to making its COVID-19 vaccine candidate available on a not-for-profit basis(eph added) for emergency pandemic use. The Company is prepared to supply its vaccine immediately upon EUA and expects to deliver enough single-dose vaccine candidate by the end of March to enable the full vaccination of more than 20 million people in the U.S. The Company plans to deliver 100 million single-dose vaccines to the U.S. during the first half of 2021.

Johnson & Johnson’s COVID-19 Vaccine Candidate
The Company’s Janssen COVID-19 Vaccine leverages the AdVac® vaccine platform, a unique and proprietary technology that was also used to develop and manufacture Janssen’s European Commission-approved Ebola vaccine regimen and construct its investigational Zika, RSV, and HIV vaccines.

Phase 3 ENSEMBLE Study Design
The Phase 3 ENSEMBLE study is a randomized, double-blind, placebo-controlled clinical trial in individuals 18 years of age and older. The study was designed to evaluate the safety and efficacy of the Company’s vaccine candidate in protecting against both moderate and severe COVID-19 disease, with assessment of efficacy as of day 14 and as of day 28 as co-primary endpoints. The study enrolled a total of 43,783 participants.

The trial, conducted in eight countries across three continents, includes a diverse and broad population, including 34% of participants over age 60.

The study enrolled 44% of participants in the United States. Seventy-four percent of participants in the U.S. are White/Caucasian; 15% are Hispanic and/or Latinx; 13% are Black/African American; 6% are Asian and 1% are Native American.

Forty-one percent of participants in the study had comorbidities associated with an increased risk for progression to severe COVID-19.

Research and development activities for the Janssen COVID-19 vaccine candidate, including the ENSEMBLE clinical trial and the delivery of doses for the U.S., have been funded with federal funds from the U.S. Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority (BARDA), under Contract No. HHSO100201700018C, and in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) at the U.S. Department of Health and Human Services (HHS).

(iow: this vaccine was fully funded already and will not cost anything)